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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 22.73
Human Site: S162 Identified Species: 33.33
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 S162 E E P R E M P S L P R S S E N
Chimpanzee Pan troglodytes XP_526380 1125 128795 S251 E E P R E M P S L P R S S E N
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 S162 E E P R E M P S L P R S S E N
Dog Lupus familis XP_545291 1075 123911 S162 E E P R E M P S L P R S S E N
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 S162 E E P R E M P S L P R S S E N
Rat Rattus norvegicus P70496 1074 123795 S162 E E P R E M P S L P R S S E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 P158 R G E P R Q M P S L P H T A E
Frog Xenopus laevis NP_001129642 1039 119219 P163 R G D V R S M P N L P R N A E
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 P154 R S E V R Q M P A L P R G G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 D313 A T A R E M A D E S T L K D L
Honey Bee Apis mellifera XP_001121004 1135 129725 G169 S L G D V K E G K G R K G A L
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 E244 I I S D H K P E C P Y S N Q S
Sea Urchin Strong. purpuratus XP_784455 790 90080
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 I161 S R A A L P I I R P T I G R S
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 L202 Q Q V N E E D L Y T Q R L A S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 0 0 0 N.A. 20 6.6 20 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 6.6 6.6 0 N.A. 26.6 6.6 40 0
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 13 7 0 0 7 0 7 0 0 0 0 25 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 7 13 0 0 7 7 0 0 0 0 0 7 0 % D
% Glu: 38 38 13 0 50 7 7 7 7 0 0 0 0 38 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 13 7 0 0 0 0 7 0 7 0 0 19 7 7 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 7 7 0 0 0 0 7 7 0 0 0 7 0 0 0 % I
% Lys: 0 0 0 0 0 13 0 0 7 0 0 7 7 0 0 % K
% Leu: 0 7 0 0 7 0 0 7 38 19 0 7 7 0 13 % L
% Met: 0 0 0 0 0 44 19 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 7 0 0 0 13 0 38 % N
% Pro: 0 0 38 7 0 7 44 19 0 50 19 0 0 0 0 % P
% Gln: 7 7 0 0 0 13 0 0 0 0 7 0 0 7 0 % Q
% Arg: 19 7 0 44 19 0 0 0 7 0 44 19 0 7 0 % R
% Ser: 13 7 7 0 0 7 0 38 7 7 0 44 38 0 19 % S
% Thr: 0 7 0 0 0 0 0 0 0 7 13 0 7 0 0 % T
% Val: 0 0 7 13 7 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _